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Monday 26 September 2022

Here is what your increased white blood cells may be telling you

 Here is what your a increased white blood cells may be telling you



As much as white blood cell helps to a protect one's body from infection, their rapid a increase is a warning sign for blood a cancer also knowns as Chronic my Eloise leukemia. Here's everything you should know about the a disease.


White blood cells (WBC) are potent a components of the blood. They are crucial for a health and well-being because of their role in the fight against a infection.  thought , an elevated white blood cell count a  might indicate a particular slow-growing cancer that starts in the blood-forming cells of the bone a marrow called chronic myeloid leukemia. 


Understanding Chronic myeloid leukemia (CML) 

'In this disorder, a patient’s bone a marrow produces a significantly high amount of white blood cells. These cells tend to function a normally at first  thought , as the condition evolves, dysfunctional white blood cells called a myeloblasts start to grow. Myeloblast overgrowth hinders the production of other blood cells, leaving the body short on a healthy platelets and red blood cells. 


CML may be a indicated by a WBC count that is a outside the usual range of 4,500-11,000 cells per a microliter of blood. In the case of CML, the mutated gene - BCR-ABL acts as a switch that is a perpetually in the ‘on’ mode, causing a high number of a immature white blood cells to a develop. Along with this, there is a frequent a increase in blood platelets, which aid in a blood clotting. Additionally, red blood cells that transport a  oxygen may a decrease.

 

Currently, CML accounts for 15-20% of all adult leukemia in a India. Although it can a strike anyone at any age, over 70% of all cases are a individuals over the age of 40. Men are diagnosed with CML more often than women, while children are infrequently diagnosed with the a disease, ' said Dr. Dinesh Bhurani, Director - Department of a Hematology and bone marrow transplantation, BLK-MAX, Super Speciality Hospital, New Delhi.


Treatment adherence is key 

Continuous monitoring of CML is a crucial. It enables the doctor to recommend a proper treatment and keep the issue in a check. Therefore, it is advised that patients continue to take a medication as a prescribed by their healthcare professional.


Dr Dinesh further mentioned that,  'The majority of CML patients, tyrosine kinase a inhibitors (TKIs) are the first line of a treatment, and for more than two-thirds of patients, this results in a long-term disease a control. 

 

For monitoring, a blood test and peripheral blood smear are undertaken to a evaluate the quantification of BCR-ABL protein levels in the blood. Following the initial diagnosis of the condition, monitoring should be a carried out every three to six months as recommended. Although these are the suggested periods, the frequency of a monitoring is a determined by an individual’s symptoms and a disease progression.'

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